| Primary | ||||||||||||
| Date | # | Opp | Score | Inn | Starter | T | W/L | Save | Versus | T | ||
| 4/5/2012 | Bos | L | 3-5 | Hernandez | R | Dotel | Cain | R | ||||
| 4/7/2012 | Bos | W | 7-6 | 10 | Lester | L | Wood | Latos | R | |||
| 4/8/2012 | Bos | W | 8-3 | Zimmermann | R | Zimmermann | Bedard | L | ||||
| 4/10/2012 | Tam | L | 3-4 | 10 | Vazquez | R | Dotel | Garcia | R | |||
| 4/11/2012 | Tam | L | 7-8 | Pineda | R | Pineda | Atchison | R | ||||
| 4/12/2012 | Tam | W | 5-0 | Hernandez | R | Hernandez | Janssen | Peacock | R | |||
| 4/13/2012 | @ | ChA | L | 1-2 | Lester | L | Lester | Jimenez | R | |||
| 4/14/2012 | @ | ChA | W | 7-4 | 16 | Zimmermann | R | Rauch | Janssen | Santana | L | |
| 4/15/2012 | @ | ChA | L | 2-5 | Vazquez | R | Vazquez | Bard | R | |||
| 4/16/2012 | @ | KC | L | 0-4 | Pineda | R | Pineda | Harden | R | |||
| 4/17/2012 | @ | KC | W | 6-3 | 11 | Hernandez | R | Dotel | Wood | Harrison | L | |
| 4/18/2012 | @ | KC | W | 3-0 | Lester | L | Lester | Bumgarner | L | |||
| 4/19/2012 | Tex | W | 6-4 | Zimmermann | R | Zimmermann | Betancourt | Garza | R | |||
| 4/20/2012 | Tex | L | 5-6 | Vazquez | R | Wood | Jurrjens | R | ||||
| 4/21/2012 | Tex | W | 6-3 | Pineda | R | Pineda | Betancourt | Frieri | R | |||
| 4/22/2012 | Tex | W | 4-0 | Hernandez | R | Hernandez | Lee | L | ||||
| 4/24/2012 | Sea | W | 6-5 | Lester | L | Hawkins | Betancourt | Weaver | R | |||
| 4/25/2012 | Sea | W | 5-1 | Zimmermann | R | Zimmermann | Chacin | R | ||||
| 4/26/2012 | Sea | W | 6-2 | Vazquez | R | Vazquez | Braden | L | ||||
| 4/27/2012 | @ | NYA | W | 3-0 | Pineda | R | Guerrier | Wood | Young | R | ||
| 4/28/2012 | @ | NYA | W | 8-2 | Hernandez | R | Hernandez | Estrada | R | |||
| 4/29/2012 | @ | NYA | W | 1-0 | Lester | L | Janssen | Betancourt | Danks | L | ||
| 4/30/2012 | KC | W | 6-5 | 10 | Zimmermann | R | Hawkins | Chapman | L | |||
| 5/1/2012 | KC | W | 8-1 | Hawkins | R | Rauch | Janssen | Minor | L | |||
| 5/2/2012 | KC | L | 2-3 | 11 | Dotel | R | Betancourt | Dempster | R | |||
| 5/4/2012 | ChA | L | 1-2 | Hernandez | R | Hernandez | Jimenez | R | ||||
| 5/5/2012 | ChA | W | 6-3 | Zimmermann | R | Betancourt | Janssen | Santana | L | |||
| 5/6/2012 | ChA | L | 7-8 | 12 | Janssen | R | Hawkins | Bard | R | |||
| 5/7/2012 | @ | Sea | W | 7-0 | Moscoso | R | Moscoso | Richard | L | |||
| 5/8/2012 | @ | Sea | L | 2-12 | Mathieson | R | Mathieson | Verlander | R | |||
| 5/9/2012 | @ | Sea | L | 5-7 | Hernandez | R | Hernandez | Weaver | R | |||
| 5/10/2012 | @ | Oak | L | 5-7 | Zimmermann | R | Zimmermann | Kendrick | R | |||
| 5/11/2012 | @ | Oak | L | 4-6 | Norris | R | Norris | Francis | L | |||
| 5/12/2012 | @ | Oak | L | 3-5 | Janssen | R | Guerrier | Pineiro | R | |||
| 5/13/2012 | @ | Oak | W | 10-8 | Mathieson | R | Mathieson | Hawkins | Kershaw | L | ||
| 5/14/2012 | @ | ChA | L | 5-14 | Hernandez | R | Hernandez | Sabathia | L | |||
| 5/15/2012 | @ | ChA | W | 4-2 | 11 | Zimmermann | R | Dotel | Jimenez | R | ||
| 5/16/2012 | Min | W | 7-0 | Norris | R | Norris | Capuano | L | ||||
| 5/17/2012 | Min | W | 7-3 | Millwood | R | Millwood | Wood | Lohse | R | |||
| 5/18/2012 | Pit | W | 4-1 | Mathieson | R | Mathieson | Betancourt | Beachy | R | |||
| 5/19/2012 | Pit | W | 9-2 | Hernandez | R | Hernandez | Wood | L | ||||
| 5/20/2012 | Pit | L | 2-10 | Zimmermann | R | Zimmermann | Vogelsong | R | ||||
| Other | |||||||||||||
| Cumulative | |||||||||||||
| Date | # | Opp | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# | ||
| 4/5/2012 | Bos | L | 3 | 5 | 0 | 1 | .000 | 0-1 | L1 | 1 | |||
| 4/7/2012 | Bos | W | Crawford | 7 | 6 | 1 | 1 | .500 | 1-1 | W1 | 2 | ||
| 4/8/2012 | Bos | W | Butler | 8 | 3 | 2 | 1 | .667 | 2-1 | W2 | 3 | ||
| 4/10/2012 | Tam | L | 3 | 4 | 2 | 2 | .500 | 2-2 | L1 | 4 | |||
| 4/11/2012 | Tam | L | 7 | 8 | 2 | 3 | .400 | 2-3 | L2 | 5 | |||
| 4/12/2012 | Tam | W | Branyan | 5 | 0 | 3 | 3 | .500 | 3-3 | W1 | 6 | ||
| 4/13/2012 | @ | ChA | L | 1 | 2 | 3 | 4 | .429 | 3-4 | L1 | 7 | ||
| 4/14/2012 | @ | ChA | W | Ross | 7 | 4 | 4 | 4 | .500 | 4-4 | W1 | 8 | |
| 4/15/2012 | @ | ChA | L | 2 | 5 | 4 | 5 | .444 | 4-5 | L1 | 9 | ||
| 4/16/2012 | @ | KC | L | 0 | 4 | 4 | 6 | .400 | 4-6 | L2 | 10 | ||
| 4/17/2012 | @ | KC | W | Ross | 6 | 3 | 5 | 6 | .455 | 5-5 | W1 | 11 | |
| 4/18/2012 | @ | KC | W | Heyward | 3 | 0 | 6 | 6 | .500 | 5-5 | W2 | 12 | |
| 4/19/2012 | Tex | W | Heyward | 6 | 4 | 7 | 6 | .538 | 5-5 | W3 | 13 | ||
| 4/20/2012 | Tex | L | 5 | 6 | 7 | 7 | .500 | 5-5 | L1 | 14 | |||
| 4/21/2012 | Tex | W | Butler | 6 | 3 | 8 | 7 | .533 | 6-4 | W1 | 15 | ||
| 4/22/2012 | Tex | W | Tulowitzki | 4 | 0 | 9 | 7 | .563 | 6-4 | W2 | 16 | ||
| 4/24/2012 | Sea | W | Ross | 6 | 5 | 10 | 7 | .588 | 7-3 | W3 | 17 | ||
| 4/25/2012 | Sea | W | Pedroia | 5 | 1 | 11 | 7 | .611 | 7-3 | W4 | 18 | ||
| 4/26/2012 | Sea | W | Ross | 6 | 2 | 12 | 7 | .632 | 8-2 | W5 | 19 | ||
| 4/27/2012 | @ | NYA | W | Brantley | 3 | 0 | 13 | 7 | .650 | 9-1 | W6 | 20 | |
| 4/28/2012 | @ | NYA | W | Rodriguez | 8 | 2 | 14 | 7 | .667 | 9-1 | W7 | 21 | |
| 4/29/2012 | @ | NYA | W | Branyan | 1 | 0 | 15 | 7 | .682 | 9-1 | W8 | 22 | |
| 4/30/2012 | KC | W | Navarro | 6 | 5 | 16 | 7 | .696 | 9-1 | W9 | 23 | ||
| 5/1/2012 | KC | W | Pedroia | 8 | 1 | 17 | 7 | .708 | 10-0 | W10 | 24 | ||
| 5/2/2012 | KC | L | 2 | 3 | 17 | 8 | .680 | 9-1 | L1 | 25 | |||
| 5/4/2012 | ChA | L | 1 | 2 | 17 | 9 | .654 | 8-2 | L2 | 26 | |||
| 5/5/2012 | ChA | W | Brantley | 6 | 3 | 18 | 9 | .667 | 8-2 | W1 | 27 | ||
| 5/6/2012 | ChA | L | 7 | 8 | 18 | 10 | .643 | 7-3 | L1 | 28 | |||
| 5/7/2012 | @ | Sea | W | 7 | 0 | 19 | 10 | .655 | 7-3 | W1 | 29 | ||
| 5/8/2012 | @ | Sea | L | 2 | 12 | 19 | 11 | .633 | 6-4 | L1 | 30 | ||
| 5/9/2012 | @ | Sea | L | 5 | 7 | 19 | 12 | .613 | 5-5 | L2 | 31 | ||
| 5/10/2012 | @ | Oak | L | 5 | 7 | 19 | 13 | .594 | 4-6 | L3 | 32 | ||
| 5/11/2012 | @ | Oak | L | 4 | 6 | 19 | 14 | .576 | 3-7 | L4 | 33 | ||
| 5/12/2012 | @ | Oak | L | 3 | 5 | 19 | 15 | .559 | 2-8 | L5 | 34 | ||
| 5/13/2012 | @ | Oak | W | Tulowitzki | 10 | 8 | 20 | 15 | .571 | 3-7 | W1 | 35 | |
| 5/14/2012 | @ | ChA | L | 5 | 14 | 20 | 16 | .556 | 3-7 | L1 | 36 | ||
| 5/15/2012 | @ | ChA | W | Branyan | 4 | 2 | 21 | 16 | .568 | 3-7 | W1 | 37 | |
| 5/16/2012 | Min | W | Tulowitzki | 7 | 0 | 22 | 16 | .579 | 4-6 | W2 | 38 | ||
| 5/17/2012 | Min | W | Branyan | 7 | 3 | 23 | 16 | .590 | 4-6 | W3 | 39 | ||
| 5/18/2012 | Pit | W | Tulowitzki | 4 | 1 | 24 | 16 | .600 | 5-5 | W4 | 40 | ||
| 5/19/2012 | Pit | W | Pedroia | 9 | 2 | 25 | 16 | .610 | 6-4 | W5 | 41 | ||
| 5/20/2012 | Pit | L | 2 | 10 | 25 | 17 | .595 | 6-4 | L1 | 42 | |||