| Primary | ||||||||||||
| Date | # | Opp | Score | Inn | Starter | T | W/L | Save | Versus | T | ||
| 4/5/2012 | @ | SD | W | 5-2 | Halladay | R | Halladay | Rivera | Buehrle | L | ||
| 4/6/2012 | @ | SD | L | 2-3 | Hudson | R | Perry | Scherzer | R | |||
| 4/7/2012 | @ | SD | W | 7-3 | Sale | L | Sale | Nova | R | |||
| 4/8/2012 | @ | SD | W | 2-1 | 15 | Worley | R | Bastardo | Cashner | R | ||
| 4/10/2012 | Pit | W | 6-0 | Halladay | R | Halladay | Beachy | R | ||||
| 4/11/2012 | Pit | W | 2-1 | Hudson | R | Perry | Wood | L | ||||
| 4/12/2012 | Pit | W | 7-1 | Sale | L | Sale | Shields | R | ||||
| 4/13/2012 | SD | W | 5-2 | Worley | R | Worley | Rivera | Cashner | R | |||
| 4/14/2012 | SD | W | 9-6 | LeCure | R | LeCure | Rivera | Wakefield | R | |||
| 4/15/2012 | SD | W | 5-2 | Halladay | R | Halladay | Buehrle | L | ||||
| 4/17/2012 | @ | Mil | L | 1-3 | Hudson | R | Hudson | Johnson | R | |||
| 4/18/2012 | @ | Mil | W | 3-1 | Sale | L | Sale | Rivera | Wainwright | R | ||
| 4/19/2012 | @ | Mil | W | 9-2 | Worley | R | Worley | Rodriguez | L | |||
| 4/20/2012 | @ | Hou | L | 4-6 | Halladay | R | Halladay | Peavy | R | |||
| 4/21/2012 | @ | Hou | W | 5-2 | Hudson | R | Hudson | Lilly | L | |||
| 4/22/2012 | @ | Hou | W | 9-4 | Sale | L | Sale | Leake | R | |||
| 4/23/2012 | Atl | W | 6-5 | Worley | R | Rivera | Zambrano | R | ||||
| 4/24/2012 | Atl | L | 1-6 | LeCure | R | LeCure | Sanchez | L | ||||
| 4/25/2012 | Atl | L | 3-5 | Halladay | R | Halladay | Germano | R | ||||
| 4/27/2012 | Was | W | 5-3 | Hudson | R | Hudson | Rivera | Medlen | R | |||
| 4/28/2012 | Was | W | 3-2 | Sale | L | Kelley | Rivera | Nicasio | R | |||
| 4/29/2012 | Was | L | 3-6 | Worley | R | Worley | Hernandez | R | ||||
| 4/30/2012 | @ | Col | W | 10-3 | LeCure | R | LeCure | Saunders | L | |||
| 5/1/2012 | @ | Col | L | 3-4 | Halladay | R | Rivera | Detwiler | L | |||
| 5/2/2012 | @ | Col | W | 7-4 | Hudson | R | Hudson | Rivera | Gee | R | ||
| 5/4/2012 | @ | ChN | W | 8-6 | Sale | L | Duensing | Bastardo | LeBlanc | L | ||
| 5/5/2012 | @ | ChN | W | 8-7 | 11 | Worley | R | Duensing | de la Rosa | L | ||
| 5/6/2012 | @ | ChN | W | 13-3 | LeCure | R | LeCure | Perry | Billingsley | R | ||
| 5/7/2012 | SF | W | 5-2 | Halladay | R | Halladay | Rivera | Kuroda | R | |||
| 5/8/2012 | SF | L | 4-8 | Hudson | R | Hudson | Gorzelanny | L | ||||
| 5/9/2012 | SF | L | 5-6 | Sale | L | Kelley | Greinke | R | ||||
| 5/11/2012 | Col | W | 4-2 | Worley | R | Perry | Rivera | Stauffer | R | |||
| 5/12/2012 | Col | L | 2-3 | Halladay | R | Perry | Saunders | L | ||||
| 5/13/2012 | Col | L | 3-7 | Hudson | R | Hudson | Detwiler | L | ||||
| 5/14/2012 | Ari | W | 6-4 | Sale | L | Sale | Duensing | Romero | L | |||
| 5/15/2012 | Ari | L | 3-5 | Worley | R | Worley | Aceves | R | ||||
| 5/16/2012 | @ | SD | W | 3-2 | LeCure | R | LeCure | Perry | Buehrle | L | ||
| 5/17/2012 | @ | SD | W | 4-1 | Halladay | R | Halladay | Rivera | Scherzer | R | ||
| 5/18/2012 | StL | W | 4-3 | Hudson | R | Kelley | Rivera | James | L | |||
| 5/19/2012 | StL | L | 2-5 | Sale | L | Perry | Strasburg | R | ||||
| 5/20/2012 | StL | W | 6-2 | Worley | R | Worley | Duensing | Runzler | L | |||
| Other | |||||||||||||
| Cumulative | |||||||||||||
| Date | # | Opp | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# | ||
| 4/5/2012 | @ | SD | W | Ramirez | 5 | 2 | 1 | 0 | 1.000 | 1-0 | W1 | 1 | |
| 4/6/2012 | @ | SD | L | 2 | 3 | 1 | 1 | .500 | 1-1 | L1 | 2 | ||
| 4/7/2012 | @ | SD | W | Rasmus | 7 | 3 | 2 | 1 | .667 | 2-1 | W1 | 3 | |
| 4/8/2012 | @ | SD | W | Sands | 2 | 1 | 3 | 1 | .750 | 3-1 | W2 | 4 | |
| 4/10/2012 | Pit | W | Lee | 6 | 0 | 4 | 1 | .800 | 4-1 | W3 | 5 | ||
| 4/11/2012 | Pit | W | Ramirez | 2 | 1 | 5 | 1 | .833 | 5-1 | W4 | 6 | ||
| 4/12/2012 | Pit | W | Konerko | 7 | 1 | 6 | 1 | .857 | 6-1 | W5 | 7 | ||
| 4/13/2012 | SD | W | Rasmus | 5 | 2 | 7 | 1 | .875 | 7-1 | W6 | 8 | ||
| 4/14/2012 | SD | W | Lee | 9 | 6 | 8 | 1 | .889 | 8-1 | W7 | 9 | ||
| 4/15/2012 | SD | W | Lee | 5 | 2 | 9 | 1 | .900 | 9-1 | W8 | 10 | ||
| 4/17/2012 | @ | Mil | L | 1 | 3 | 9 | 2 | .818 | 8-2 | L1 | 11 | ||
| 4/18/2012 | @ | Mil | W | Rasmus | 3 | 1 | 10 | 2 | .833 | 9-1 | W1 | 12 | |
| 4/19/2012 | @ | Mil | W | Rasmus | 9 | 2 | 11 | 2 | .846 | 9-1 | W2 | 13 | |
| 4/20/2012 | @ | Hou | L | 4 | 6 | 11 | 3 | .786 | 8-2 | L1 | 14 | ||
| 4/21/2012 | @ | Hou | W | Konerko | 5 | 2 | 12 | 3 | .800 | 8-2 | W1 | 15 | |
| 4/22/2012 | @ | Hou | W | Rasmus | 9 | 4 | 13 | 3 | .813 | 8-2 | W2 | 16 | |
| 4/23/2012 | Atl | W | Lee | 6 | 5 | 14 | 3 | .824 | 8-2 | W3 | 17 | ||
| 4/24/2012 | Atl | L | 1 | 6 | 14 | 4 | .778 | 7-3 | L1 | 18 | |||
| 4/25/2012 | Atl | L | 3 | 5 | 14 | 5 | .737 | 6-4 | L2 | 19 | |||
| 4/27/2012 | Was | W | Freese | 5 | 3 | 15 | 5 | .750 | 6-4 | W1 | 20 | ||
| 4/28/2012 | Was | W | Montero | 3 | 2 | 16 | 5 | .762 | 7-3 | W2 | 21 | ||
| 4/29/2012 | Was | L | 3 | 6 | 16 | 6 | .727 | 6-4 | L1 | 22 | |||
| 4/30/2012 | @ | Col | W | Tabata | 10 | 3 | 17 | 6 | .739 | 6-4 | W1 | 23 | |
| 5/1/2012 | @ | Col | L | 3 | 4 | 17 | 7 | .708 | 6-4 | L1 | 24 | ||
| 5/2/2012 | @ | Col | W | Lee | 7 | 4 | 18 | 7 | .720 | 6-4 | W1 | 25 | |
| 5/4/2012 | @ | ChN | W | Montero | 8 | 6 | 19 | 7 | .731 | 6-4 | W2 | 26 | |
| 5/5/2012 | @ | ChN | W | Rasmus | 8 | 7 | 20 | 7 | .741 | 6-4 | W3 | 27 | |
| 5/6/2012 | @ | ChN | W | Konerko | 13 | 3 | 21 | 7 | .750 | 7-3 | W4 | 28 | |
| 5/7/2012 | SF | W | Rasmus | 5 | 2 | 22 | 7 | .759 | 8-2 | W5 | 29 | ||
| 5/8/2012 | SF | L | 4 | 8 | 22 | 8 | .733 | 7-3 | L1 | 30 | |||
| 5/9/2012 | SF | L | 5 | 6 | 22 | 9 | .710 | 6-4 | L2 | 31 | |||
| 5/11/2012 | Col | W | Montero | 4 | 2 | 23 | 9 | .719 | 7-3 | W1 | 32 | ||
| 5/12/2012 | Col | L | 2 | 3 | 23 | 10 | .697 | 6-4 | L1 | 33 | |||
| 5/13/2012 | Col | L | 3 | 7 | 23 | 11 | .676 | 6-4 | L2 | 34 | |||
| 5/14/2012 | Ari | W | Andrus | 6 | 4 | 24 | 11 | .686 | 6-4 | W1 | 35 | ||
| 5/15/2012 | Ari | L | 3 | 5 | 24 | 12 | .667 | 5-5 | L1 | 36 | |||
| 5/16/2012 | @ | SD | W | Tabata | 3 | 2 | 25 | 12 | .676 | 5-5 | W1 | 37 | |
| 5/17/2012 | @ | SD | W | Andrus | 4 | 1 | 26 | 12 | .684 | 5-5 | W2 | 38 | |
| 5/18/2012 | StL | W | Freese | 4 | 3 | 27 | 12 | .692 | 5-5 | W3 | 39 | ||
| 5/19/2012 | StL | L | 2 | 5 | 27 | 13 | .675 | 5-5 | L1 | 40 | |||
| 5/20/2012 | StL | W | 6 | 2 | 28 | 13 | .683 | 6-4 | W1 | 41 | |||