| Primary | ||||||||||||
| Date | # | Opp | Score | Inn | Starter | T | W/L | Save | Versus | T | ||
| 3/28/2012 | @ | Oak | L | 1-2 | Verlander | R | Verlander | Kershaw | L | |||
| 3/29/2012 | @ | Oak | W | 9-1 | Weaver | R | Weaver | Hanson | R | |||
| 4/6/2012 | @ | Oak | L | 1-4 | Verlander | R | Verlander | Kershaw | L | |||
| 4/7/2012 | @ | Oak | L | 1-2 | Weaver | R | Weaver | Hanson | R | |||
| 4/9/2012 | @ | Tex | W | 5-3 | Chacin | R | Chacin | Madson | Jurrjens | R | ||
| 4/10/2012 | @ | Tex | L | 5-15 | Braden | L | Braden | Morton | R | |||
| 4/11/2012 | @ | Tex | L | 0-1 | 10 | Verlander | R | Thornton | Lee | L | ||
| 4/12/2012 | @ | Tex | L | 2-5 | Weaver | R | Weaver | Lincecum | R | |||
| 4/13/2012 | Oak | W | 4-3 | Chacin | R | Clippard | Madson | Francis | L | |||
| 4/14/2012 | Oak | W | 2-1 | Braden | L | Madson | Kershaw | L | ||||
| 4/15/2012 | Oak | L | 2-3 | 11 | Richard | L | Rodriguez | Hanson | R | |||
| 4/17/2012 | Cle | W | 4-3 | Verlander | R | Verlander | Belisario | Lowe | R | |||
| 4/18/2012 | Cle | L | 5-12 | Weaver | R | Weaver | Haren | R | ||||
| 4/19/2012 | Cle | W | 2-1 | Chacin | R | Chacin | Madson | Collmenter | R | |||
| 4/20/2012 | ChA | L | 1-4 | Braden | L | Braden | Bard | R | ||||
| 4/21/2012 | ChA | W | 4-1 | Richard | L | Richard | Madson | Matsuzaka | R | |||
| 4/22/2012 | ChA | L | 0-2 | Verlander | R | Verlander | Sabathia | L | ||||
| 4/24/2012 | @ | Det | L | 5-6 | Weaver | R | Weaver | Lester | L | |||
| 4/25/2012 | @ | Det | L | 1-5 | Chacin | R | Chacin | Zimmermann | R | |||
| 4/26/2012 | @ | Det | L | 2-6 | Braden | L | Braden | Vazquez | R | |||
| 4/27/2012 | @ | Tor | L | 3-15 | Richard | L | Richard | Bailey | R | |||
| 4/28/2012 | @ | Tor | W | 15-8 | Verlander | R | Verlander | Torres | L | |||
| 4/29/2012 | @ | Tor | W | 7-1 | Weaver | R | Weaver | Vargas | L | |||
| 4/30/2012 | @ | Tam | W | 4-1 | Chacin | R | Chacin | Madson | Ring | L | ||
| 5/1/2012 | @ | Tam | W | 7-5 | Braden | L | Braden | Madson | Buckner | R | ||
| 5/2/2012 | @ | Tam | W | 11-7 | Richard | L | Burnett | Paulino | R | |||
| 5/3/2012 | @ | Tam | L | 3-4 | Verlander | R | Verlander | Blanton | R | |||
| 5/4/2012 | Min | W | 4-3 | 10 | Weaver | R | Madson | Liriano | L | |||
| 5/5/2012 | Min | L | 2-6 | Chacin | R | Chacin | Harang | R | ||||
| 5/6/2012 | Min | L | 3-12 | Braden | L | Braden | Capuano | L | ||||
| 5/7/2012 | Det | L | 0-7 | Richard | L | Richard | Moscoso | R | ||||
| 5/8/2012 | Det | W | 12-2 | Verlander | R | Verlander | Mathieson | R | ||||
| 5/9/2012 | Det | W | 7-5 | Weaver | R | Weaver | Madson | Hernandez | R | |||
| 5/11/2012 | @ | NYA | W | 6-5 | 10 | Chacin | R | Madson | Clippard | Price | L | |
| 5/12/2012 | @ | NYA | W | 4-3 | Braden | L | Ondrusek | Thornton | Hellickson | R | ||
| 5/13/2012 | @ | NYA | L | 4-10 | Richard | L | Richard | Oswalt | R | |||
| 5/14/2012 | @ | Bos | W | 8-2 | Verlander | R | Verlander | Pettitte | L | |||
| 5/15/2012 | @ | Bos | L | 2-3 | Weaver | R | Weaver | Bedard | L | |||
| 5/16/2012 | @ | Cle | L | 2-8 | Chacin | R | Chacin | Collmenter | R | |||
| 5/17/2012 | @ | Cle | L | 5-7 | Braden | L | Clippard | de la Rosa | R | |||
| 5/18/2012 | @ | Col | W | 9-5 | Richard | L | Richard | Detwiler | L | |||
| 5/19/2012 | @ | Col | W | 4-0 | Verlander | R | Verlander | Hoover | R | |||
| 5/20/2012 | @ | Col | L | 3-6 | Weaver | R | Weaver | Wuertz | R | |||
| Other | |||||||||||||
| Cumulative | |||||||||||||
| Date | # | Opp | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# | ||
| 3/28/2012 | @ | Oak | L | 1 | 2 | 0 | 1 | .000 | 0-1 | L1 | 1 | ||
| 3/29/2012 | @ | Oak | W | Ethier | 9 | 1 | 1 | 1 | .500 | 1-1 | W1 | 2 | |
| 4/6/2012 | @ | Oak | L | 1 | 4 | 1 | 2 | .333 | 1-2 | L1 | 3 | ||
| 4/7/2012 | @ | Oak | L | 1 | 2 | 1 | 3 | .250 | 1-3 | L2 | 4 | ||
| 4/9/2012 | @ | Tex | W | Pujols | 5 | 3 | 2 | 3 | .400 | 2-3 | W1 | 5 | |
| 4/10/2012 | @ | Tex | L | 5 | 15 | 2 | 4 | .333 | 2-4 | L1 | 6 | ||
| 4/11/2012 | @ | Tex | L | 0 | 1 | 2 | 5 | .286 | 2-5 | L2 | 7 | ||
| 4/12/2012 | @ | Tex | L | 2 | 5 | 2 | 6 | .250 | 2-6 | L3 | 8 | ||
| 4/13/2012 | Oak | W | Pujols | 4 | 3 | 3 | 6 | .333 | 3-6 | W1 | 9 | ||
| 4/14/2012 | Oak | W | Trout | 2 | 1 | 4 | 6 | .400 | 4-6 | W2 | 10 | ||
| 4/15/2012 | Oak | L | 2 | 3 | 4 | 7 | .364 | 4-6 | L1 | 11 | |||
| 4/17/2012 | Cle | W | Pujols | 4 | 3 | 5 | 7 | .417 | 4-6 | W1 | 12 | ||
| 4/18/2012 | Cle | L | 5 | 12 | 5 | 8 | .385 | 4-6 | L1 | 13 | |||
| 4/19/2012 | Cle | W | Jones | 2 | 1 | 6 | 8 | .429 | 5-5 | W1 | 14 | ||
| 4/20/2012 | ChA | L | 1 | 4 | 6 | 9 | .400 | 4-6 | L1 | 15 | |||
| 4/21/2012 | ChA | W | Cairo | 4 | 1 | 7 | 9 | .438 | 5-5 | W1 | 16 | ||
| 4/22/2012 | ChA | L | 0 | 2 | 7 | 10 | .412 | 5-5 | L1 | 17 | |||
| 4/24/2012 | @ | Det | L | 5 | 6 | 7 | 11 | .389 | 5-5 | L2 | 18 | ||
| 4/25/2012 | @ | Det | L | 1 | 5 | 7 | 12 | .368 | 4-6 | L3 | 19 | ||
| 4/26/2012 | @ | Det | L | 2 | 6 | 7 | 13 | .350 | 3-7 | L4 | 20 | ||
| 4/27/2012 | @ | Tor | L | 3 | 15 | 7 | 14 | .333 | 3-7 | L5 | 21 | ||
| 4/28/2012 | @ | Tor | W | Jones | 15 | 8 | 8 | 14 | .364 | 3-7 | W1 | 22 | |
| 4/29/2012 | @ | Tor | W | Jones | 7 | 1 | 9 | 14 | .391 | 4-6 | W2 | 23 | |
| 4/30/2012 | @ | Tam | W | Pujols | 4 | 1 | 10 | 14 | .417 | 4-6 | W3 | 24 | |
| 5/1/2012 | @ | Tam | W | Ethier | 7 | 5 | 11 | 14 | .440 | 5-5 | W4 | 25 | |
| 5/2/2012 | @ | Tam | W | 11 | 7 | 12 | 14 | .462 | 5-5 | W5 | 26 | ||
| 5/3/2012 | @ | Tam | L | 3 | 4 | 12 | 15 | .444 | 5-5 | L1 | 27 | ||
| 5/4/2012 | Min | W | Young | 4 | 3 | 13 | 15 | .464 | 6-4 | W1 | 28 | ||
| 5/5/2012 | Min | L | 2 | 6 | 13 | 16 | .448 | 6-4 | L1 | 29 | |||
| 5/6/2012 | Min | L | 3 | 12 | 13 | 17 | .433 | 6-4 | L2 | 30 | |||
| 5/7/2012 | Det | L | 0 | 7 | 13 | 18 | .419 | 6-4 | L3 | 31 | |||
| 5/8/2012 | Det | W | Ethier | 12 | 2 | 14 | 18 | .438 | 6-4 | W1 | 32 | ||
| 5/9/2012 | Det | W | Ethier | 7 | 5 | 15 | 18 | .455 | 6-4 | W2 | 33 | ||
| 5/11/2012 | @ | NYA | W | Ethier | 6 | 5 | 16 | 18 | .471 | 6-4 | W3 | 34 | |
| 5/12/2012 | @ | NYA | W | Pujols | 4 | 3 | 17 | 18 | .486 | 6-4 | W4 | 35 | |
| 5/13/2012 | @ | NYA | L | 4 | 10 | 17 | 19 | .472 | 5-5 | L1 | 36 | ||
| 5/14/2012 | @ | Bos | W | Uribe | 8 | 2 | 18 | 19 | .486 | 6-4 | W1 | 37 | |
| 5/15/2012 | @ | Bos | L | 2 | 3 | 18 | 20 | .474 | 5-5 | L1 | 38 | ||
| 5/16/2012 | @ | Cle | L | 2 | 8 | 18 | 21 | .462 | 5-5 | L2 | 39 | ||
| 5/17/2012 | @ | Cle | L | 5 | 7 | 18 | 22 | .450 | 5-5 | L3 | 40 | ||
| 5/18/2012 | @ | Col | W | Young | 9 | 5 | 19 | 22 | .463 | 6-4 | W1 | 41 | |
| 5/19/2012 | @ | Col | W | Ethier | 4 | 0 | 20 | 22 | .476 | 6-4 | W2 | 42 | |
| 5/20/2012 | @ | Col | L | 3 | 6 | 20 | 23 | .465 | 5-5 | L1 | 43 | ||